Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773035 | 0.77 | ALDH1A1 (0.48) | NAAAEPHX1DNM1TSHRHCAR2 | |
| SCHEMBL8773024 | 0.75 | ALDH1A1 (0.38) | EPHX1DNM1TSHRTHRATHRB | |
| SCHEMBL8773015 | 0.75 | ALDH1A1 (0.42) | NAAAEPHX1DNM1TSHRDGKA | |
| SCHEMBL8773042 | 0.75 | ALDH1A1 (0.42) | NAAADNM1TSHRDGKAHCAR2 | |
| SCHEMBL10615595 | 0.72 | TSHR (0.50) | NAAACES2EPHX1TSHRTHRB | |
| SCHEMBL9461649 | 0.70 | NAAA (0.48) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL8512927 | 0.70 | NAAA (0.48) | NAAACES2EPHX1TSHRHCAR2 | |
| SCHEMBL11454255 | 0.70 | CES2 (0.52) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL5698083 | 0.70 | CES2 (0.52) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL3004605 | 0.70 | NAAA (0.48) | NAAACES2EPHX1TSHRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030739-A1 | POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | WO | disclosed |