Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247395 | 1.00 | DNM1 (0.45) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| SCHEMBL28988014 | 1.00 | DNM1 (0.45) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| SCHEMBL28984653 | 1.00 | DNM1 (0.45) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| SCHEMBL3966579 | 1.00 | DNM1 (0.45) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| SCHEMBL561147 | 1.00 | DNM1 (0.45) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| Ammonia Solution, Strong SCHEMBL5185843 | 0.98 | DNM1 (0.44) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| Cetostearyl Alcohol SCHEMBL936993 | 0.91 | LMNA (0.46) | DNM1SPHK1THRBTSHRMEN1 | |
| SCHEMBL25305244 | 0.89 | CNR1 (0.49) | SPHK1LPAR1LPAR3LPAR2 | |
| SCHEMBL9549590 | 0.86 | DNM1 (0.48) | DNM1SPHK1LPAR1LPAR3LPAR2 | |
| SCHEMBL9549569 | 0.86 | DNM1 (0.48) | DNM1SPHK1LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748798-B1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB (US) | 2010-05-05 | — | — | EP | claimed |
| EP-1748798-B1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB (US) | 2010-05-05 | — | — | EP | disclosed |