SCHEMBL561147

SCHEMBL561147

CCCCCCCCCCCCCCCCCCOC(CC)N(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.45
SPHK1 Q9NYA1 1/20 0.42
LPAR1 Q92633 4/20 0.35
LPAR3 Q9UBY5 4/20 0.35
LPAR2 Q9HBW0 1/20 0.35
THRB P10828 2/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3243536 1.00 DNM1 (0.45) DNM1SPHK1LPAR1LPAR3LPAR2
SCHEMBL3247395 1.00 DNM1 (0.45) DNM1SPHK1LPAR1LPAR3LPAR2
SCHEMBL28988014 1.00 DNM1 (0.45) DNM1SPHK1LPAR1LPAR3LPAR2
SCHEMBL28984653 1.00 DNM1 (0.45) DNM1SPHK1LPAR1LPAR3LPAR2
SCHEMBL3966579 1.00 DNM1 (0.45) DNM1SPHK1LPAR1LPAR3LPAR2
Ammonia Solution, Strong SCHEMBL5185843 0.98 DNM1 (0.44) DNM1SPHK1LPAR1LPAR3LPAR2
Cetostearyl Alcohol SCHEMBL936993 0.91 LMNA (0.46) DNM1SPHK1THRBTSHRMEN1
SCHEMBL25305244 0.89 CNR1 (0.49) SPHK1LPAR1LPAR3LPAR2
SCHEMBL9549590 0.86 DNM1 (0.48) DNM1SPHK1LPAR1LPAR3LPAR2
SCHEMBL9549569 0.86 DNM1 (0.48) DNM1SPHK1LPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9579277-B2 Conditioning composition for hair KAO GERMANY GMBH (DE) 2017-02-28 US claimed
US-20150224048-A1 Conditioning Composition for Hair KAO GERMANY GMBH (DE) 2015-08-13 US claimed
US-7892526-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-02-22 US claimed
EP-1433465-B1 Hair cosmetic composition KAO CORP (JP) 2010-07-21 EP claimed
US-20090181059-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2009-07-16 US claimed
EP-1574201-B1 Composition comprising benzyloxyethanol as preservative KAO CORP (JP) 2007-12-19 EP claimed
US-20040166084-A1 Hair cosmetic composition KAO CORPORATION (JP) 2004-08-26 US claimed
EP-1433465-A2 Hair cosmetic composition Kao Corporation (JP) 2004-06-30 EP claimed
WO-2025105181-A1 CLEANING AGENT COMPOSITION 花王株式会社 2025-05-22 WO disclosed
EP-3498811-B1 SURFACTANT COMPOSITION KAO CORP (JP) 2025-02-12 EP disclosed
EP-3467079-B1 SURFACTANT COMPOSITION KAO CORP (JP) 2024-09-11 EP disclosed
US-20240101985-A1 ENGINEERED MEGANUCLEASES SPECIFIC FOR RECOGNITION SEQUENCES IN THE PCSK9 GENE PRECISION BIOSCIENCES, INC. (US) 2024-03-28 US disclosed
US-20240101986-A1 ENGINEERED MEGANUCLEASES SPECIFIC FOR RECOGNITION SEQUENCES IN THE PCSK9 GENE PRECISION BIOSCIENCES, INC. (US) 2024-03-28 US disclosed
US-11904052-B2 Methods for ameliorating infusion reactions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-02-20 US disclosed
US-4899521-A AROMATIC SULFONAMIDE W. R. GRACE & CO. - CONN. (US) 1990-02-13 US disclosed
US-4898771-A Agent for imparting antistatic characteristics to a thermoplastic polymer and a thermoplastic polymer composition containing the agent W. R. GRACE & CO.-CONN. (US) 1990-02-06 US disclosed
US-4882894-A MULTILAYER POLYAMIDES, POLYETHYLENE WITH BENZENESULFONAMIDES W. R. GRACE & CO.-CONN. (US) 1989-11-28 US disclosed
US-4800115-A POLYOXYALKYLENE GLYCOLS ETHERIFIED, POLYETHYLENE, MONOGLYCERIDES W. R. GRACE & CO. (US) 1989-01-24 US disclosed
EP-0264269-A1 Use of thermoplastic polymer composition film containing an antistatic agent W.R. Grace & Co.-Conn. (US) 1988-04-20 EP disclosed
EP-0264270-A2 Thermoplastic polymer composition having antistatic characteristics W.R. Grace & Co.-Conn. (US) 1988-04-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224048-A1 Conditioning Composition for Hair H1-4, H1-0, H1-10 DNM1 1138/4885SPHK1 2529/4885LPAR1 923/4885
US-20090181059-A1 HAIR COSMETIC COMPOSITION H1-0, H1-2, SHH DNM1 2082/4885SPHK1 566/4885LPAR1 758/4885
US-11904052-B2 Methods for ameliorating infusion reactions IL2, CD47, IL5 DNM1 1346/4885SPHK1 751/4885LPAR1 921/4885
US-20040166084-A1 Hair cosmetic composition H1-0, H1-2, SHH DNM1 1907/4885SPHK1 603/4885LPAR1 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.