Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 10/20 | 0.55 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | CD44 | P16070 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247434 | 0.87 | CD44 (0.53) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL11478327 | 0.83 | PNMT (0.55) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL27788108 | 0.83 | PNMT (0.57) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL11481975 | 0.83 | PNMT (0.55) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL11481980 | 0.80 | PNMT (0.53) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL11475778 | 0.80 | PNMT (0.51) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL11744452 | 0.80 | PNMT (0.51) | PNMTPRCPCD44MAOBADRA2A | |
| SCHEMBL11740703 | 0.80 | PNMT (0.51) | PNMTPRCPCD44MAOB | |
| SCHEMBL11117006 | 0.78 | TTR (0.41) | PNMT | |
| SCHEMBL4961562 | 0.75 | BCL2L1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227803-B1 | COMPOUNDS FOR INHIBITING IAPP-ASSOCIATED AMYLOID DEPOSITS | BELLUS HEALTH INTERNATIONAL LTD (CH) | 2010-05-05 | — | — | EP | claimed |
| US-6562836-B1 | Islet amyloid polypeptide (IAPP) is known to be capable of forming fibrils which are deposited in the pancreas of patients wtih type II diabetes | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 2003-05-13 | — | — | US | claimed |
| CN-108697499-A | Labeled nucleotide analogs, reaction mixtures, and sequencing methods and systems | 加利福尼亚太平洋生物科学股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108603219-A | Modified nucleotide reagent | 加利福尼亚太平洋生物科学股份有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108472121-A | Protected dye-labelled reagents | 加利福尼亚太平洋生物科学股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-1227803-B1 | COMPOUNDS FOR INHIBITING IAPP-ASSOCIATED AMYLOID DEPOSITS | BELLUS HEALTH INTERNATIONAL LTD (CH) | 2010-05-05 | — | — | EP | disclosed |
| WO-2010002483-A1 | OPTIONALLY CONDENSED DIHYDRO PYRIDINE, DIHYDROPYRIMIDINE AND DIHYDRO PYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2009006580-A1 | OPTIONALLY CONDENSED DIHYDROPYRIDINE, DIHYDROPYRIMIDINE AND DIHYDROPYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |