Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916810 | 0.88 | BCL2L1 (0.47) | TTRBCL2L1BADKDM4EALDH1A1 | |
| SCHEMBL4961562 | 0.88 | BCL2L1 (0.52) | TTRBCL2L1BADKDM4ETSHR | |
| SCHEMBL24631329 | 0.81 | TTR (0.42) | TTRCES1MYCHSD17B10FABP4 | |
| Ammonia Solution, Strong SCHEMBL27823874 | 0.79 | TTR (0.41) | TTRMYCHSD17B10FABP4CCNA2 | |
| SCHEMBL24631174 | 0.79 | TTR (0.41) | TTRMYCHSD17B10FABP4CCNA2 | |
| SCHEMBL3243586 | 0.78 | PNMT (0.55) | PNMT | |
| SCHEMBL3247434 | 0.78 | CD44 (0.53) | KDM4EPNMT | |
| SCHEMBL5367202 | 0.78 | CYP11B1 (0.46) | TTRKDM4EHSD17B10HPGDFABP4 | |
| SCHEMBL7787658 | 0.77 | DRD2 (0.38) | TTR | |
| SCHEMBL7787573 | 0.77 | TRPV1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452945-A | HYDROXYL GROUP CONTAINING ADDITION POLYMER AND ALKYLATED MELAMINE-FORMALDEHYDE CROSSLINKING AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-05 | — | — | US | disclosed |