Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 5/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | RXRG | P48443 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716663 | 0.80 | CD44 (0.45) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6964619 | 0.76 | SLC6A4 (0.49) | BCL2L1BADRXRARXRBRXRG | |
| SCHEMBL6964699 | 0.76 | HTR1A (0.49) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6966923 | 0.75 | HTR1A (0.48) | HTR2CHTR2B | |
| SCHEMBL3125795 | 0.73 | SIGMAR1 (0.48) | BCL2L1BAD | |
| Hydrochloric Acid SCHEMBL6962641 | 0.73 | SLC6A4 (0.49) | RXRARXRBRXRGHTR2CHTR2B | |
| SCHEMBL2096545 | 0.72 | CTSV (0.41) | MCHR1 | |
| SCHEMBL911314 | 0.72 | SLC6A4 (0.49) | — | |
| SCHEMBL911313 | 0.72 | SLC6A4 (0.49) | — | |
| SCHEMBL31312989 | 0.72 | BCL2L1 (0.54) | BCL2L1BADRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |