SCHEMBL3243983

SCHEMBL3243983

C=CO[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
AKT1 P31749 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7631134 0.84 ALDH1A1 (0.38) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL11050697 0.83 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL13835936 0.80 ESR1 (0.37) ALDH1A1TSHRESR1ESR2
SCHEMBL11659900 0.80 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL11659904 0.80 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL3786225 0.78 TSHR (0.33) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL10456261 0.78 ESR1 (0.35) ALDH1A1TSHRESR1ESR2
SCHEMBL4144211 0.77 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL8431820 0.77 MAPT (0.34) ESR1ESR2
SCHEMBL3891715 0.75 POLB (0.32) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962470-B1 Production process for polyvinyl ether and catalyst used for the process NIPPON CATALYTIC CHEM IND (JP) 2004-03-24 EP claimed
EP-0962470-A1 Production process for polyvinyl ether and catalyst used for the process NIPPON SHOKUBAI CO., LTD. (JP) 1999-12-08 EP claimed
WO-2013003318-A1 PROCESS FOR PREPARING VINYL CHLOROFORMATE BAUSCH & LOMB INCORPORATED (US) 2013-01-03 WO disclosed
US-7745654-B2 Process for the preparation of vinyl- or allyl-containing compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-29 US disclosed
EP-1840115-A2 Process for the preparation of vinyl- or allyl-containing compounds Daicel Chemical Industries, Ltd. (JP) 2007-10-03 EP disclosed
US-20070213549-A1 Process for the preparation of vinyl- or allyl-containing compounds DAICEL CHEMICAL INDUSTRIES, LTD. 2007-09-13 US disclosed
EP-0962470-B1 Production process for polyvinyl ether and catalyst used for the process NIPPON CATALYTIC CHEM IND (JP) 2004-03-24 EP disclosed
US-6235859-B1 USING AN ACID CLAY MINERAL SUBJECTED TO ACID TREATMENT AS A CATALYST TO POLYMERIZE VINYL ETHER. NIPPON SHOKUBAH CO LTD (JP) 2001-05-22 US disclosed
EP-0962470-A1 Production process for polyvinyl ether and catalyst used for the process NIPPON SHOKUBAI CO., LTD. (JP) 1999-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213549-A1 Process for the preparation of vinyl- or allyl-containing compounds ESRRB, NR0B2, ESRRA ALDH1A1 1891/4885TSHR 968/4885AKT1 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.