SCHEMBL3786225

SCHEMBL3786225

C=CO[Si](O)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
AKT1 P31749 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3243983 0.78 ALDH1A1 (0.38) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL7631134 0.78 ALDH1A1 (0.38) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL13835936 0.74 ESR1 (0.37) TSHRALDH1A1ESR1ESR2
SCHEMBL10456261 0.73 ESR1 (0.35) TSHRALDH1A1ESR1ESR2
SCHEMBL11050697 0.73 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL688585 0.72 ESR1 (0.37) TSHRALDH1A1ESR1ESR2
SCHEMBL9419485 0.71 ESR1 (0.35) ESR1ESR2
SCHEMBL27587595 0.70 ESR1 (0.36) TSHRALDH1A1ESR1ESR2ALOX15
SCHEMBL10456554 0.70 ESR1 (0.33) TSHRALDH1A1ESR1ESR2
SCHEMBL3891715 0.70 POLB (0.32) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165615-A1 PROCESS FOR PRODUCING POLYSILOXANES AND USE OF THE SAME ZETTA RESEARCH AND DEVELOPMENT LLC - RPO SERIES (US) 2013-06-27 US claimed
EP-2078051-A1 PROCESS FOR PRODUCING POLYSILOXANES AND USE OF THE SAME RPO PTY Limited (AU) 2009-07-15 EP claimed
US-20090088547-A1 Process for producing polysiloxanes and use of the same RPO PTY LIMITED (AU) 2009-04-02 US claimed
WO-2008046142-A1 PROCESS FOR PRODUCING POLYSILOXANES AND USE OF THE SAME RPO PTY LIMITED (AU) 2008-04-24 WO claimed
US-20100213490-A1 SEALING COMPOSITION FOR LIGHT EMITTING DEVICE AND LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-08-26 US disclosed
US-7498085-B2 Epoxy/silicone mixed resin composition and light-emitting semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-03-03 US disclosed
US-7276562-B2 Epoxy-silicone mixed resin composition and light-emitting semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-10-02 US disclosed
US-20050244649-A1 Epoxy-silicone mixed resin composition and light-emitting semiconductor device SHIN-ETSU CHEMICAL CO., LTD. 2005-11-03 US disclosed
US-20050129957-A1 Epoxy/silicone mixed resin composition and light-emitting semiconductor device SHIN-ETSU CHEMICAL CO., LTD. 2005-06-16 US disclosed