SCHEMBL3244018

SCHEMBL3244018

Cc1c(C)c(O)c2ccccc2c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
KDM4E B2RXH2 4/20 0.50
PKM P14618 1/20 0.50
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GAA P10253 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
CYP1A2 P05177 2/20 0.45
IDO1 P14902 1/20 0.45
DAO P14920 1/20 0.45
DDO Q99489 1/20 0.45
POLB P06746 2/20 0.42
MCL1 Q07820 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
NPC1 O15118 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3668045 0.92 HTT (0.48) LMNAHTTKDM4EPKMMEN1
SCHEMBL27705068 0.88 LMNA (0.50) LMNAHTTKDM4EPKMMEN1
SCHEMBL9716925 0.88 LMNA (0.50) LMNAHTTKDM4EPKMMEN1
SCHEMBL2065604 0.86 LMNA (0.48) LMNAHTTKDM4EPKMMEN1
SCHEMBL26565516 0.85 LMNA (0.43) LMNAHTTKDM4EPKMMEN1
SCHEMBL10870053 0.85 PKM (0.50) LMNAHTTKDM4EPKMMEN1
SCHEMBL4625912 0.85 HTT (0.43) LMNAHTTKDM4EPKMMEN1
SCHEMBL1101881 0.85 LMNA (0.52) LMNAHTTKDM4EPKMMEN1
SCHEMBL25280341 0.82 DAO (0.47) LMNAHTTKDM4EPKMMEN1
SCHEMBL12377557 0.82 LMNA (0.45) LMNAHTTKDM4EPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010014361-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI- INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES EDISON PHARMACEUTICALS, INC. (US) 2010-02-04 WO claimed
US-20100029784-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES AMPERE LIFE SCIENCES, INC. 2010-02-04 US claimed
WO-2023151942-A1 DEVICE FOR CONVERTING THERMAL ENERGY OF AN EXTERNAL HEAT SOURCE INTO ELECTRICAL ENERGY HAESE FRANK (DE) 2023-08-17 WO disclosed
EP-4227604-A1 DEVICE FOR CONVERTING THERMAL ENERGY OF AN EXTERNAL HEAT SOURCE INTO ELECTRICAL ENERGY Haese, Frank (DE) 2023-08-16 EP disclosed
EP-3620459-B1 PHOSPHORUS-CONTAINING PHENOLIC COMPOUND, PHOSPHORUS-CONTAINING EPOXY RESIN, CURABLE RESIN COMPOSITION THEREOF, OR EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-05-24 EP disclosed
WO-2010035000-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2010-04-01 WO disclosed
WO-2010014361-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI- INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES EDISON PHARMACEUTICALS, INC. (US) 2010-02-04 WO disclosed
WO-2010014361-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI- INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES EDISON PHARMACEUTICALS, INC. (US) 2010-02-04 WO disclosed
US-20100029784-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES AMPERE LIFE SCIENCES, INC. 2010-02-04 US disclosed
US-20100029784-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES AMPERE LIFE SCIENCES, INC. 2010-02-04 US disclosed
US-20100029784-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES AMPERE LIFE SCIENCES, INC. 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029784-A1 NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES NFE2L2, NQO1, POT1 LMNA 156/4885HTT 123/4885KDM4E 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.