Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244785 | 0.88 | CIT (0.57) | ROCK2F3DGAT2ROCK1CIT | |
| SCHEMBL3246832 | 0.85 | ROCK2 (0.72) | ROCK2ROCK1CIT | |
| SCHEMBL3129372 | 0.85 | ROCK2 (0.47) | ROCK2F3DGAT2ROCK1CIT | |
| SCHEMBL13391340 | 0.83 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL3240812 | 0.82 | ROCK2 (0.51) | ROCK2F3ROCK1ALDH1A1 | |
| SCHEMBL3245171 | 0.80 | ROCK2 (0.69) | ROCK2ROCK1 | |
| SCHEMBL3256534 | 0.79 | ROCK2 (0.62) | ROCK2ROCK1CIT | |
| SCHEMBL3130579 | 0.78 | JAK3 (0.47) | ROCK2ROCK1CITBRD4ALDH1A1 | |
| SCHEMBL3239562 | 0.76 | ROCK2 (0.59) | ROCK2ROCK1 | |
| SCHEMBL3245457 | 0.76 | ROCK2 (0.68) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |