SCHEMBL3244368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2296183	0.81	HDAC6 (1.00)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL8108193	0.81	HDAC3 (0.58)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL7018973	0.80	HDAC3 (0.73)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL5551328	0.80	DAO (0.48)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL3253253	0.79	HDAC3 (0.56)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL3247389	0.77	PLOD2 (0.60)	HPGDALDH1A1CASP3SENP7PLOD2
	SCHEMBL7219808	0.76	HDAC3 (0.59)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL28588115	0.75	HDAC4 (0.61)	HDAC4HDAC6HDAC1HDAC3HPGD
	SCHEMBL28407046	0.74	PLOD2 (0.47)	HDAC4HDAC6HDAC1HDAC3ERCC5
	SCHEMBL10876692	0.74	GSK3B (0.59)	HPGDALDH1A1CASP3SENP7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.