Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244846 | 0.83 | HTR1A (0.40) | HTR1ADRD2DRD4 | |
| SCHEMBL3244851 | 0.83 | HTR1A (0.40) | HTR1ADRD2DRD4 | |
| SCHEMBL3244940 | 0.71 | DRD2 (0.37) | HTR1ADRD2DRD4 | |
| SCHEMBL3243831 | 0.70 | KMT2A (0.44) | DRD2DRD4LMNA | |
| SCHEMBL3246780 | 0.67 | CYP3A4 (0.41) | DRD2DRD4LMNA | |
| SCHEMBL3246762 | 0.67 | CYP3A4 (0.41) | DRD2DRD4LMNA | |
| SCHEMBL17442799 | 0.66 | DRD2 (0.55) | DRD2DRD4LMNA | |
| SCHEMBL29723776 | 0.63 | NOTUM (0.51) | LMNA | |
| SCHEMBL7549846 | 0.63 | DRD2 (0.53) | DRD2DRD4 | |
| SCHEMBL3832260 | 0.63 | CYP3A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102204-B1 | NEW AMINOPYRROLO[1,2- A]INDOLE ET AMINOPYRIDAZINO[1,6-A]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SERVIER LAB (FR) | 2010-05-05 | — | — | EP | disclosed |