SCHEMBL3245044

SCHEMBL3245044

CC1(CC(Cl)Cl)NC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADAMTS5 Q9UNA0 16/20 0.41
ADAM17 P78536 11/20 0.41
ADAMTS4 O75173 5/20 0.41
MMP2 P08253 5/20 0.39
MMP14 P50281 3/20 0.39
MMP13 P45452 2/20 0.39
ADAMTS1 Q9UHI8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5827546 0.84 ADAMTS5 (0.39) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL10576904 0.81 ADAMTS5 (0.42) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL2138946 0.81 ADAMTS5 (0.42) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL10574702 0.81 ADAMTS5 (0.42) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL11598413 0.79 SMN1; SMN2 (0.39) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL9190559 0.76 ADAMTS5 (0.43) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL1363544 0.76 SMN1; SMN2 (0.42) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL17871080 0.73 ADAMTS5 (0.49) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL19691698 0.73 ADAMTS5 (0.49) ADAMTS5ADAM17ADAMTS4MMP2MMP14
SCHEMBL28353437 0.73 ADAMTS5 (0.49) ADAMTS5ADAM17ADAMTS4MMP2MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335153-B Formulation delivery system with solid chemical components W·M·巴尔公司 2025-06-10 CN claimed
US-20240082886-A1 FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-03-14 US claimed
US-11833552-B2 Formulation delivery system having a solid chemistry W.M. BARR & COMPANY, INC. (US) 2023-12-05 US claimed
CN-115335153-A Formulation delivery system with solid chemical components W·M·巴尔公司 2022-11-11 CN claimed
EP-4076762-A1 A FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY W.M. Barr & Company, Inc. (US) 2022-10-26 EP claimed
US-20210187560-A1 FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY W.M. BARR & COMPANY, INC. 2021-06-24 US claimed
WO-2021127219-A1 A FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY W.M. BARR & COMPANY, INC. (US) 2021-06-24 WO claimed
US-9371479-B2 Controlled release biocides in oilfield applications SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-06-21 US claimed
US-20120285693-A1 CONTROLLED RELEASE BIOCIDES IN OILFIELD APPLICATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2012-11-15 US claimed
WO-2012125890-A2 CONTROLLED RELEASE BIOCIDES IN OILFIELD APPLICATIONS SCHLUMBERGER CANADA LIMITED (CA) 2012-09-20 WO claimed
EP-1556547-B1 ADDITIVE AND METHOD FOR AVOIDING OR AT LEAST REDUCING DEPOSITS IN WATER BEARING AND/OR CONTACTING INDUSTRIAL SYSTEMS POHLEN ALFRED (LU) 2010-05-12 EP claimed
US-RE39021-E1 Hydantoin-enhanced halogen efficacy in pulp and paper applications LONZA INC. (US) 2006-03-21 US claimed
EP-1556547-A1 ADDITIVE AND METHOD FOR AVOIDING OR AT LEAST REDUCING DEPOSITS IN WATER BEARING AND/OR CONTACTING INDUSTRIAL SYSTEMS Pohlen, Alfred (LU) 2005-07-27 EP claimed
WO-2004031481-A1 ADDITIVE AND METHOD FOR AVOIDING OR AT LEAST REDUCING DEPOSITS IN WATER BEARING AND/OR CONTACTING INDUSTRIAL SYSTEMS POHLEN ALFRED (LU) 2004-04-15 WO claimed
EP-0785909-B1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA AG (US) 2003-04-16 EP claimed
EP-0785909-A4 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA AG (US) 1998-02-25 EP claimed
EP-0785909-A1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA, INC. (US) 1997-07-30 EP claimed
US-5565109-A SLIMICIDES LONZA INC. (US) 1996-10-15 US claimed
WO-1996011882-A1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA INC. (US) 1996-04-25 WO claimed
CN-115335153-B Formulation delivery system with solid chemical components W·M·巴尔公司 2025-06-10 CN disclosed
EP-3402674-B1 FRIABLE SHELL MICROCAPSULES, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2024-11-20 EP disclosed
US-20240082886-A1 FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-03-14 US disclosed
US-11833552-B2 Formulation delivery system having a solid chemistry W.M. BARR & COMPANY, INC. (US) 2023-12-05 US disclosed
CN-115335153-A Formulation delivery system with solid chemical components W·M·巴尔公司 2022-11-11 CN disclosed
EP-4076762-A1 A FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY W.M. Barr & Company, Inc. (US) 2022-10-26 EP disclosed
US-11396000-B2 Friable shell microcapsules, process for preparing the same and method of use thereof ISP INVESTMENTS LLC (US) 2022-07-26 US disclosed
CN-110248549-B Use of encapsulated chlorine bleach particles to reduce gas evolution during dispensing 埃科莱布美国股份有限公司 2021-11-19 CN disclosed
US-20210230478-A1 PARTICULATE COMPOSITIONS CONTAINING OIL FIELD CHEMICALS EXXONMOBIL RES & ENG CO (US) 2021-07-29 US disclosed
WO-2021127219-A1 A FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY W.M. BARR & COMPANY, INC. (US) 2021-06-24 WO disclosed
US-20210187560-A1 FORMULATION DELIVERY SYSTEM HAVING A SOLID CHEMISTRY W.M. BARR & COMPANY, INC. 2021-06-24 US disclosed
CN-108778730-B Friable shell microcapsules, methods of making and methods of using the same ISP投资有限公司 2021-02-09 CN disclosed
US-10739269-B2 Detection of trace chemicals in oil and gas applications BAKER HUGHES, A GE COMPANY, LLC (US) 2020-08-11 US disclosed
US-20200165509-A1 METHODS FOR DIAGNOSING, MONITORING AND MITIGATING MICROBIOLOGICALLY INFLUENCED CORROSION EXXONMOBIL RES & ENG CO (US) 2020-05-28 US disclosed
WO-2020081275-A1 DETECTION OF TRACE CHEMICALS IN OIL AND GAS APPLICATIONS BAKER HUGHES, A GE COMPANY, LLC (US) 2020-04-23 WO disclosed
US-20200124534-A1 DETECTION OF TRACE CHEMICALS IN OIL AND GAS APPLICATIONS BAKER HUGHES, A GE COMPANY, LLC (US) 2020-04-23 US disclosed
WO-2020041128-A1 CAPSULES, SYSTEMS AND METHODS FOR TARGETED DELIVERY OF CHEMICALS INTO MULTIPHASE ENVIRONMENTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-02-27 WO disclosed
US-20200063028-A1 CAPSULES, SYSTEMS AND METHODS FOR TARGETED DELIVERY OF CHEMICALS INTO MULTIPHASE ENVIRONMENTS EXXONMOBIL RES & ENG CO (US) 2020-02-27 US disclosed
EP-3568019-A1 USE OF AN ENCAPSULATED CHLORINE BLEACH PARTICLE TO REDUCE GAS EVOLUTION DURING DISPENSING Ecolab USA Inc. (US) 2019-11-20 EP disclosed
CN-110248549-A Use of encapsulated chlorine bleach particles to reduce gas evolution during dispensing 埃科莱布美国股份有限公司 2019-09-17 CN disclosed
US-10287474-B2 Rare earth-containing compounds to enhance performance of downhole treatment compositions BAKER HUGHES, A GE COMPANY, LLC (US) 2019-05-14 US disclosed
US-20190054440-A1 FRIABLE SHELL MICROCAPSULES, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2019-02-21 US disclosed
US-10138418-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHES, A GE COMPANY, LLC (US) 2018-11-27 US disclosed
EP-3402674-A1 FRIABLE SHELL MICROCAPSULES, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP Investments LLC (US) 2018-11-21 EP disclosed
CN-108778730-A Frangible shell microcapsules, preparation method and its application method ISP投资有限公司 2018-11-09 CN disclosed
US-10087354-B2 Rare earth-containing compounds to enhance performance of downhole treatment compositions BAKER HUGHES, A GE COMPANY, LLC (US) 2018-10-02 US disclosed
US-20180202138-A1 Toilet Bowl Disinfectant Tissue JOHNSON FRANCIS (US) 2018-07-19 US disclosed
WO-2018132292-A1 USE OF AN ENCAPSULATED CHLORINE BLEACH PARTICLE TO REDUCE GAS EVOLUTION DURING DISPENSING ECOLAB USA INC. (US) 2018-07-19 WO disclosed
US-20180192643-A1 USE OF AN ENCAPSULATED CHLORINE BLEACH PARTICLE TO REDUCE GAS EVOLUTION DURING DISPENSING ECOLAB USA INC. 2018-07-12 US disclosed
US-9994756-B2 Segregating fluids, methods of making, and methods of use BAKER HUGHES, A GE COMPANY, LLC (US) 2018-06-12 US disclosed
US-9951261-B2 Cement spacer system for wellbores, methods of making, and methods of use BAKER HUGHES, A GE COMPANY, LLC (US) 2018-04-24 US disclosed
US-20180044579-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME BAKER HUGHES, A GE COMPANY, LLC (US) 2018-02-15 US disclosed
US-9828844-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHTES, a GE company, LLC (US) 2017-11-28 US disclosed
US-9809742-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHES, A GE COMPANY, LLC (US) 2017-11-07 US disclosed
US-9802846-B2 Treating and recylcing oilfield waste water BAKER HUGHES, A GE COMPANY, LLC (US) 2017-10-31 US disclosed
EP-3234060-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME Baker Hughes Incorporated (US) 2017-10-25 EP disclosed
US-9796914-B2 Hydraulic fracturing composition, method for making and use of same BAKER HUGHES INCORPORATED (US) 2017-10-24 US disclosed
US-20170240790-A1 RARE EARTH-CONTAINING COMPOUNDS TO ENHANCE PERFORMANCE OF DOWNHOLE TREATMENT COMPOSITIONS BAKER HUGHES INCORPORATED (US) 2017-08-24 US disclosed
US-9670080-B2 Composition and method for treating oilfield water BAKER HUGHES INCORPORATED (US) 2017-06-06 US disclosed
US-9650559-B2 Cement isolation fluids for wellbores, methods of making, and methods of use BAKER HUGHES INCORPORATED (US) 2017-05-16 US disclosed
WO-2017070016-A1 RARE EARTH-CONTAINING COMPOUNDS TO ENHANCE PERFORMANCE OF DOWNHOLE TREATMENT COMPOSITIONS BAKER HUGHES INCORPORATED (US) 2017-04-27 WO disclosed
US-20170114266-A1 RARE EARTH-CONTAINING COMPOUNDS TO ENHANCE PERFORMANCE OF DOWNHOLE TREATMENT COMPOSITIONS BAKER HUGHES INCORPORATED (US) 2017-04-27 US disclosed
US-20170044035-A1 OILFIELD WASTEWATER TREATMENT BAKER HUGHES INCORPORATED (US) 2017-02-16 US disclosed
WO-2016154376-A1 APPLICATION OF CHLORINE DIOXIDE TO SUBSURFACE WELLS BAKER HUGHES INCORPORATED (US) 2016-09-29 WO disclosed
US-20160280988-A1 APPLICATION OF CHLORINE DIOXIDE TO SUBSURFACE WELLS BAKER HUGHES INCORPORATED (US) 2016-09-29 US disclosed
WO-2016144645-A1 CEMENT SPACER SYSTEM FOR WELLBORES, METHODS OF MAKING, AND METHODS OF USE BAKER HUGHES INCORPORATED (US) 2016-09-15 WO disclosed
US-20160265306-A1 CEMENT ISOLATION FLUIDS FOR WELLBORES, METHODS OF MAKING, AND METHODS OF USE BAKER HUGHES INCORPORATED (US) 2016-09-15 US disclosed
WO-2016144644-A1 CEMENT ISOLATION FLUIDS FOR WELLBORES, METHODS OF MAKING, AND METHODS OF USE BAKER HUGHES INCORPORATED (US) 2016-09-15 WO disclosed
WO-2016144643-A1 SEGREGATING FLUIDS, METHODS OF MAKING, AND METHODS OF USE BAKER HUGHES INCORPORATED (US) 2016-09-15 WO disclosed
US-20160264838-A1 CEMENT SPACER SYSTEM FOR WELLBORES, METHODS OF MAKING, AND METHODS OF USE BAKER HUGHES INCORPORATED (US) 2016-09-15 US disclosed
US-20160264837-A1 SEGREGATING FLUIDS, METHODS OF MAKING, AND METHODS OF USE BAKER HUGHES INCORPORATED (US) 2016-09-15 US disclosed
WO-2016100048-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME BAKER HUGHES INCORPORATED (US) 2016-06-23 WO disclosed
US-9371479-B2 Controlled release biocides in oilfield applications SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-06-21 US disclosed
US-20150096751-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME BAKER HUGHES INCORPORATED (US) 2015-04-09 US disclosed
US-20140374104-A1 COMPOSITION AND METHOD FOR TREATING OILFIELD WATER BAKER HUGHES INCORPORATED (US) 2014-12-25 US disclosed
US-20140374103-A1 TREATING AND RECYLCING OILFIELD WASTE WATER BAKER HUGHES INCORPORATED (US) 2014-12-25 US disclosed
US-20140332213-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME BAKER HUGHES INCORPORATED (US) 2014-11-13 US disclosed
US-20140332214-A1 HYDRAULIC FRACTURING COMPOSITION, METHOD FOR MAKING AND USE OF SAME BAKER HUGHES INCORPORATED (US) 2014-11-13 US disclosed
US-20120285693-A1 CONTROLLED RELEASE BIOCIDES IN OILFIELD APPLICATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2012-11-15 US disclosed
WO-2012125890-A2 CONTROLLED RELEASE BIOCIDES IN OILFIELD APPLICATIONS SCHLUMBERGER CANADA LIMITED (CA) 2012-09-20 WO disclosed
US-RE39021-E1 Hydantoin-enhanced halogen efficacy in pulp and paper applications LONZA INC. (US) 2006-03-21 US disclosed
EP-0785909-B1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA AG (US) 2003-04-16 EP disclosed
EP-0785909-A4 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA AG (US) 1998-02-25 EP disclosed
US-5702684-A Method of use of compositions of biocides and fluorescent indicators to control microbial growth NALCO CHEMICAL COMPANY (US) 1997-12-30 US disclosed
EP-0785909-A1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA, INC. (US) 1997-07-30 EP disclosed
US-5565109-A SLIMICIDES LONZA INC. (US) 1996-10-15 US disclosed
WO-1996011882-A1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA INC. (US) 1996-04-25 WO disclosed
WO-1996011882-A1 HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS LONZA INC. (US) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180192643-A1 USE OF AN ENCAPSULATED CHLORINE BLEACH PARTICLE TO REDUCE GAS EVOLUTION DURING DISPENSING CLIC1, CLCN2, CLIC4 ADAMTS5 4494/4885ADAM17 4472/4885ADAMTS4 4651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.