Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 16/20 | 0.39 |
| ▸ | MMP2 | P08253 | 10/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 3/20 | 0.36 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11676230 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL13209004 | 0.78 | LMNA (0.48) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL542612 | 0.78 | LMNA (0.48) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL2185650 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL1132700 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL8342071 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL13209009 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL15427305 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL4107323 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL3245044 | 0.76 | ADAMTS5 (0.41) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8066977-B2 | Agent for permanent hair waving containing heterocyclic mercapto compound | SHOWA DENKO K.K. (JP) | 2011-11-29 | — | — | US | disclosed |
| CN-101184528-B | Permanent waving agent containing heterocyclic mercapto compound | SHOWA DENKO KK | 2010-12-29 | — | — | CN | disclosed |
| EP-1883454-B1 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO KK (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | SHOWA DENKO K.K. (JP) | 2009-08-20 | — | — | US | disclosed |
| CN-101184528-A | Permanent waving agent containing heterocyclic mercapto compound | SHOWA DENKO KK (JP) | 2008-05-21 | — | — | CN | disclosed |
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |
| US-20060051846-A1 | Process for producing l-alpha-methylcysteine derivative | KANEKA CORPORATION (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1541692-A1 | PROCESS FOR PRODUCING L-a-METHYLCYSTEINE DERIVATIVE | KANEKA CORPORATION (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | NSD3, WNT3, MSRB3 | SMN1; SMN2 3473/4885NPSR1 773/4885ALDH1A1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.