Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246666 | 0.93 | METTL3 (0.39) | METTL3PCSK9P2RX7RIPK1HIF1A | |
| SCHEMBL3247049 | 0.93 | METTL3 (0.39) | METTL3PCSK9P2RX7RIPK1HIF1A | |
| SCHEMBL3246516 | 0.92 | METTL3 (0.38) | METTL3PCSK9CFD | |
| SCHEMBL3239576 | 0.91 | METTL3 (0.38) | METTL3PCSK9P2RX7RIPK1HIF1A | |
| SCHEMBL3232649 | 0.89 | METTL3 (0.46) | METTL3P2RX7CFDMAPT | |
| SCHEMBL1042873 | 0.89 | METTL3 (0.45) | METTL3CFDMAPT | |
| SCHEMBL3246472 | 0.88 | METTL3 (0.39) | METTL3CFDSLC22A12MAPT | |
| SCHEMBL3234775 | 0.87 | METTL3 (0.40) | METTL3PCSK9P2RX7CFDMAPT | |
| SCHEMBL3241137 | 0.87 | METTL3 (0.40) | METTL3PCSK9P2RX7HIF1AMAPT | |
| SCHEMBL3240311 | 0.87 | METTL3 (0.42) | METTL3PCSK9P2RX7HIF1ACFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |