Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239576 | 0.94 | METTL3 (0.38) | METTL3PCSK9CD38TOP1 | |
| SCHEMBL3246666 | 0.93 | METTL3 (0.39) | METTL3PCSK9CD38CFD | |
| SCHEMBL3245181 | 0.92 | METTL3 (0.40) | METTL3PCSK9CFD | |
| SCHEMBL3247049 | 0.89 | METTL3 (0.39) | METTL3PCSK9PKMSMN1; SMN2CFD | |
| SCHEMBL1044455 | 0.89 | METTL3 (0.42) | METTL3PCSK9CD38CFDTOP1 | |
| SCHEMBL3246472 | 0.86 | METTL3 (0.39) | METTL3CFD | |
| SCHEMBL3232649 | 0.86 | METTL3 (0.46) | METTL3CFD | |
| SCHEMBL3246482 | 0.85 | METTL3 (0.38) | METTL3 | |
| SCHEMBL3234775 | 0.84 | METTL3 (0.40) | METTL3PCSK9CFD | |
| SCHEMBL3243220 | 0.84 | METTL3 (0.38) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |