Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243386 | 0.94 | METTL3 (0.46) | METTL3PYGLCFDRXFP1EGFR | |
| SCHEMBL3242029 | 0.92 | METTL3 (0.43) | METTL3PYGLCFDRXFP1P2RX7 | |
| SCHEMBL1046596 | 0.92 | METTL3 (0.50) | METTL3KMT2AMEN1SMN1; SMN2PYGL | |
| SCHEMBL3243285 | 0.92 | METTL3 (0.50) | METTL3KMT2AMEN1SMN1; SMN2PYGL | |
| SCHEMBL3239627 | 0.86 | METTL3 (0.47) | METTL3KMT2AMEN1THRBMAPT | |
| SCHEMBL3246669 | 0.86 | METTL3 (0.54) | METTL3CFDRXFP1CD274HTR2C | |
| SCHEMBL3241758 | 0.86 | METTL3 (0.43) | METTL3THRBRXFP1CD274ALDH1A1 | |
| SCHEMBL1041873 | 0.85 | METTL3 (0.56) | METTL3PYGLCFD | |
| SCHEMBL1041874 | 0.85 | METTL3 (0.56) | METTL3PYGLCFD | |
| SCHEMBL3235235 | 0.85 | METTL3 (0.53) | METTL3THRBCFDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |