Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240923 | 0.82 | MET (0.38) | ALDH1A1KDM4EMETCCKBRMAPK1 | |
| SCHEMBL3248520 | 0.81 | HDAC1 (0.38) | ALDH1A1MAPTGAAHDAC1HDAC8 | |
| SCHEMBL13521678 | 0.81 | HTT (0.39) | ALDH1A1KDM4EGAAAAK1MAPK1 | |
| SCHEMBL30507033 | 0.80 | FNTA (0.38) | KDM4EFNTAFNTBMAPTAAK1 | |
| SCHEMBL25316077 | 0.80 | FNTA (0.38) | KDM4EFNTAFNTBMAPTAAK1 | |
| SCHEMBL30506707 | 0.79 | HDAC1 (0.34) | ALDH1A1KDM4EMAPTGAAHDAC1 | |
| SCHEMBL25316939 | 0.79 | HDAC1 (0.34) | ALDH1A1KDM4EMAPTGAAHDAC1 | |
| SCHEMBL3310478 | 0.79 | MAPT (0.54) | ALDH1A1METMAPTGAAHDAC1 | |
| SCHEMBL3240957 | 0.78 | GRIN2B (0.41) | METMAPK1 | |
| SCHEMBL23320864 | 0.76 | MAPT (0.44) | ALDH1A1METMAPTGAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |