Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25161712 | 0.89 | TAAR1 (0.48) | CYP1A2CYP2A6TAAR1GFERCYP19A1 | |
| SCHEMBL20611212 | 0.88 | CYP1A2 (0.46) | CYP1A2CYP2A6TAAR1GFERCYP19A1 | |
| SCHEMBL16356150 | 0.85 | CYP1A2 (0.43) | CYP1A2CYP2A6TAAR1GFERCYP19A1 | |
| SCHEMBL10890416 | 0.82 | CASP1 (0.46) | GFERCYP19A1CASP1MAOAMAOB | |
| SCHEMBL4810025 | 0.81 | ESR1 (0.52) | TAAR1GFERCYP19A1CASP1MAOA | |
| SCHEMBL4810383 | 0.81 | MAOB (0.59) | CYP1A2CYP2A6TAAR1GFERCYP19A1 | |
| SCHEMBL3251668 | 0.81 | CYP19A1 (0.57) | TAAR1CYP19A1MAOB | |
| SCHEMBL14193174 | 0.81 | ALDH1A1 (0.48) | GFERCYP19A1MAOAMAOBMEN1 | |
| Hydrochloric Acid SCHEMBL3244731 | 0.80 | BLM (0.52) | TAAR1GFERCYP19A1CASP1MAOA | |
| Hydrochloric Acid SCHEMBL3249498 | 0.80 | CYP19A1 (0.56) | TAAR1CYP19A1MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685091-B1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | PROCTER & GAMBLE (US) | 2010-05-19 | — | — | EP | claimed |
| US-7361198-B2 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | WELLA AG (DE) | 2008-04-22 | — | — | US | claimed |
| US-20060047172-A1 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | Wella GmbH (DE) | 2006-03-02 | — | — | US | claimed |
| EP-1685091-B1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | PROCTER & GAMBLE (US) | 2010-05-19 | — | — | EP | disclosed |
| US-7361198-B2 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | WELLA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| US-7361198-B2 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | WELLA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| US-7361198-B2 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | WELLA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| EP-1685091-A1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | Wella Aktiengesellschaft (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20060047172-A1 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | Wella GmbH (DE) | 2006-03-02 | — | — | US | disclosed |
| WO-2005051889-A1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047172-A1 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | DDT, NQO1, MDH2 | CYP1A2 359/4885CYP2A6 454/4885TAAR1 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.