SCHEMBL3246349

SCHEMBL3246349

COc1ccc(OP(=O)(O)Oc2ccc(OC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA7 P43166 1/20 0.52
ACP3 P15309 1/20 0.50
HPGD P15428 1/20 0.48
PKM P14618 1/20 0.47
HTT P42858 1/20 0.47
PLK1 P53350 1/20 0.47
PARP1 P09874 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP2 Q9UGN5 1/20 0.45
PARP4 Q9UKK3 1/20 0.45
MMP2 P08253 1/20 0.44
LMNA P02545 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL31047198 0.98 CES2 (0.52) CES2CES1CA1CA2CA12
SCHEMBL22322005 0.92 PKM (0.59) CES2CES1ACP3HPGDPKM
SCHEMBL9702463 0.87 ACP3 (0.44) CES2CES1CA1CA2CA12
SCHEMBL17169181 0.87 CYP2C19 (0.46) CES2CES1CA1CA2ACP3
SCHEMBL3219196 0.86 SRC (0.60) CES2CES1CA1CA2CA12
SCHEMBL8388389 0.84 ALDH1A1 (0.44) CES2CES1CA1CA2CA12
SCHEMBL27542662 0.84 SMN1; SMN2 (0.43) CES2CES1CA1CA2CA12
Nitrogen SCHEMBL28174348 0.84 ACP3 (0.42) CES2CES1CA1CA2CA12
Hydrochloric Acid SCHEMBL28893937 0.84 SRC (0.58) CES2CES1CA1CA2CA12
SCHEMBL28074568 0.84 CYP2C19 (0.60) CES2CES1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136918-A Method for preparing 4- (2, 2-diaryl vinyl) thiophosphorus/phosphonate 岳阳凯茂化工材料有限公司 2025-06-13 CN claimed
CN-118778354-B Photosensitive resin composition and application thereof 深圳先进电子材料国际创新研究院 2025-05-23 CN claimed
WO-2025007970-A1 REGENERATION TREATMENT METHOD FOR DEGRADABLE HIGH POLYMER MATERIAL AND USE 复旦大学 2025-01-09 WO claimed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN claimed
CN-118778354-A Photosensitive resin composition and application thereof 深圳先进电子材料国际创新研究院 2024-10-15 CN claimed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN claimed
CN-112441974-B Chiral o-diamine compound and chiral N-heterocyclic carbene compound, and preparation methods and applications thereof 中国科学院化学研究所 2023-01-03 CN claimed
CN-113683565-A Asymmetric hydrogenation kinetic resolution method of racemic polysubstituted dihydroisoquinoline 中国科学院化学研究所 2021-11-23 CN claimed
CN-113583042-A Preparation method of phosphoryl fluoride compound 烟台大学 2021-11-02 CN claimed
CN-110437280-B Novel method for preparing 2 '-iodo [1, 1' -biaryl ] -2-organic phosphonate compound 湖南理工学院 2021-09-07 CN claimed
CN-110590835-B Method for preparing 2-iodo-1-phosphoryl substituted alkane compound by high-efficiency double functionalization of olefin 湖南理工学院 2021-09-07 CN claimed
CN-112441974-A Chiral o-diamine compound and chiral N-heterocyclic carbene compound, and preparation methods and applications thereof 中国科学院化学研究所 2021-03-05 CN claimed
CN-107602609-B Method for preparing organic phosphate compound by using P (O) -OH compound and methyl-containing substituted aromatic hydrocarbon 湖南理工学院 2020-07-21 CN claimed
CN-110590835-A Method for preparing 2-iodo-1-phosphoryl substituted alkane compound by high-efficiency double functionalization of olefin 湖南理工学院 2019-12-20 CN claimed
CN-120136918-A Method for preparing 4- (2, 2-diaryl vinyl) thiophosphorus/phosphonate 岳阳凯茂化工材料有限公司 2025-06-13 CN disclosed
CN-118778354-B Photosensitive resin composition and application thereof 深圳先进电子材料国际创新研究院 2025-05-23 CN disclosed
WO-2025007970-A1 REGENERATION TREATMENT METHOD FOR DEGRADABLE HIGH POLYMER MATERIAL AND USE 复旦大学 2025-01-09 WO disclosed
WO-1992005219-A1 FORMULATIONS OF CELLULOSE ESTERS WITH ARYLENE-BIS(DIARYL PHOSPHATE)S EASTMAN KODAK COMPANY (US) 1992-04-02 WO disclosed
US-4258142-A ADDING A PHENYL PHOSPHATE AND METAL COMPOUND ARGUS CHEMICAL CORP. (US) 1981-03-24 US disclosed
US-4138553-A 3-Methylene cephalosporanic acid derivatives and process for preparation thereof TEIJIN LIMITED (JP) 1979-02-06 US disclosed