Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40648 | 0.82 | ALDH1A1 (0.42) | AOC3NPC1RAB9ATDP1CES1 | |
| SCHEMBL3240867 | 0.75 | TAAR1 (0.48) | TAAR1AOC3MEN1NPC1RAB9A | |
| SCHEMBL2087539 | 0.74 | TAAR1 (0.52) | TAAR1AOC3MEN1NPC1RAB9A | |
| SCHEMBL5409509 | 0.74 | TAAR1 (0.52) | TAAR1AOC3MLYCDMEN1NPC1 | |
| Iodide SCHEMBL31550892 | 0.72 | TAAR1 (0.50) | TAAR1AOC3MLYCDMEN1NPC1 | |
| Bromide SCHEMBL29093974 | 0.72 | TAAR1 (0.50) | TAAR1AOC3MLYCDMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL5408807 | 0.72 | TAAR1 (0.50) | TAAR1AOC3MLYCDMEN1NPC1 | |
| SCHEMBL29029103 | 0.71 | TAAR1 (0.48) | TAAR1AOC3MLYCDMEN1NPC1 | |
| SCHEMBL5449888 | 0.71 | ALOX5 (0.49) | TAAR1AOC3MEN1NPC1RAB9A | |
| SCHEMBL10501436 | 0.71 | AOC3 (0.55) | TAAR1AOC3MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450138-B | Preparation of intermidiates of 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC | 2015-04-08 | — | — | CN | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | TAAR1 436/4885AOC3 662/4885MLYCD 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.