SCHEMBL3246904

SCHEMBL3246904

Cc1ccc(C2CC(=O)OC2=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
THRB P10828 2/20 0.55
HPGD P15428 2/20 0.55
GLA P06280 1/20 0.55
RECQL P46063 1/20 0.55
SIRT2 Q8IXJ6 5/20 0.52
ALDH2 P05091 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017610 0.90 CTRC (0.47) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL12172558 0.81 CTRB1 (0.44) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL10690598 0.81 MEN1 (0.55) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL31121830 0.81 CTRC (0.49) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL11263779 0.80 ALDH1A1 (0.64) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL576832 0.80 CTRC (0.61) ALDH1A1MAPTKMT2AHPGDSIRT2
SCHEMBL8274960 0.80 CTRC (0.61) ALDH1A1MAPTKMT2AHPGDSIRT2
SCHEMBL2608115 0.79 PLAU (0.41) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL13014967 0.77 CTRC (0.45) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL13829430 0.77 CTRC (0.38) ALDH1A1MAPTMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382409-B2 Amine functionalized polymer BRIDGESTONE CORPORATION (JP) 2016-07-05 US disclosed
EP-1805223-B1 FUNCTIONALIZED POLYMER WITH LINKING GROUP BRIDGESTONE CORP (JP) 2014-12-24 EP disclosed
US-20140148527-A1 AMINE FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (US) 2014-05-29 US disclosed
US-8642706-B2 Amine functionalized polymer BRIDGESTONE CORPORATION (JP) 2014-02-04 US disclosed
US-20120142813-A1 AMINE FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2012-06-07 US disclosed
EP-1772466-B1 Amine functionalized polymer BRIDGESTONE CORP (JP) 2010-05-05 EP disclosed
EP-1772466-A1 Amine functionalized polymer Bridgestone Corporation (JP) 2007-04-11 EP disclosed
US-20070078232-A1 Amine functionalized polymer BRIDGESTONE CORPORATION (JP) 2007-04-05 US disclosed