Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.59 |
| ▸ | TUBB | P07437 | 2/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275502 | 0.89 | NR4A2 (0.71) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL3275504 | 0.86 | MEN1 (0.65) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL18824256 | 0.83 | MAP2 (0.62) | NR4A2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31305695 | 0.82 | NR4A2 (0.57) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL5220303 | 0.81 | KDM4E (0.66) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL31019418 | 0.81 | KDM4E (0.66) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL721793 | 0.80 | MAP2 (0.58) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3262790 | 0.80 | KDM4E (0.53) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL3253095 | 0.80 | KDM4E (0.56) | NR4A2MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL8528482 | 0.79 | NR4A2 (0.67) | NR4A2MEN1KMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651639-B1 | BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS | ARPIDA AG (CH) | 2010-05-26 | — | — | EP | disclosed |
| US-7524854-B2 | Benzofuran derivatives and their use in the treatment of microbial infections | ARPIDA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20060154943-A1 | Benzofuran derivatives and their use in the treatment of microbial infections | ARPIDA AG (CH) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154943-A1 | Benzofuran derivatives and their use in the treatment of microbial infections | DCXR, NLRP3, NISCH | NR4A2 2263/4885MEN1 4151/4885KMT2A 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.