SCHEMBL3247350

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4144293	0.86	CCNA2 (0.48)	ROCK2ROCK1BRD4POLBNPC1
	SCHEMBL4155814	0.81	ALDH1A1 (0.50)	MAPTNPC1RAB9ACDK2KDM4E
	SCHEMBL3247351	0.79	BRD4 (0.44)	ROCK2ROCK1BRD4POLBNPC1
	SCHEMBL1600742	0.79	CCNA2 (0.42)	ROCK2ROCK1CDK2CCNA2CCNA1
	SCHEMBL5412686	0.77	BRD4 (0.47)	ROCK2ROCK1BRD4MAPTCDK2
	SCHEMBL8062076	0.77	CCNA2 (0.43)	ROCK2ROCK1NPC1RAB9ACDK2
	SCHEMBL25286660	0.76	NOS1 (0.44)	NPC1RAB9ACDK2CCNA2CCNA1
	SCHEMBL13999326	0.76	CCNA2 (0.45)	ROCK2ROCK1TDP1MAPTNPC1
	SCHEMBL2192636	0.76	TRPA1 (0.43)	NPC1RAB9ACDK2CCNA2CCNA1
	SCHEMBL31692339	0.76	TRPA1 (0.43)	NPC1RAB9ACDK2CCNA2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.