Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Oxyquinoline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.81 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | COMT | P21964 | 3/20 | 0.81 |
| ▸ | MMP2 | P08253 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | METAP2 | P50579 | 1/20 | 0.81 |
| ▸ | METAP1 | P53582 | 1/20 | 0.81 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL11030481 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL29358129 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL29390000 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL11030474 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL9625423 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL48928 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL29598375 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL11030477 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL406261 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL6081972 | 0.98 | KDM4E (0.96) | KDM4EALOX12COMTMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 728 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658816-B | N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides | 拜尔农作物科学股份公司 | 2023-05-02 | — | — | CN | claimed |
| CN-107926985-B | Compositions comprising biological control agents and fungicides | 拜尔农作物科学股份公司 | 2021-02-02 | — | — | CN | claimed |
| EP-3488700-B1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2020-12-16 | — | — | EP | claimed |
| CN-104507317-B | Composition comprising a biological control agent and a fungicide, use thereof, kit | 拜尔农作物科学股份公司 | 2019-11-15 | — | — | CN | claimed |
| EP-3010893-B1 | ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-10-02 | — | — | EP | claimed |
| EP-3488700-A1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2019-05-29 | — | — | EP | claimed |
| EP-2854552-B1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE SELECTED FROM INHIBITORS OF AMINO ACID OR PROTEIN BIOSYNTHESIS, INHIBITORS OF ATP PRODUCTION AND INHIBITORS OF THE CELL WALL SYNTHESIS | BAYER CROPSCIENCE AG (DE) | 2019-05-08 | — | — | EP | claimed |
| EP-3409120-A1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2018-12-05 | — | — | EP | claimed |
| EP-3395171-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-10-31 | — | — | EP | claimed |
| CN-108669088-A | Include the composition of biocontrol agent and the fungicide selected from Cell wall synthesis inhibitor | 拜耳作物科学股份公司 | 2018-10-19 | — | — | CN | claimed |
| WO-2012143127-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | BAYER CROPSCIENCES AG (DE) | 2012-10-26 | — | — | WO | claimed |
| EP-2494867-A1 | Halogen-substituted compounds in combination with fungicides | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | claimed |
| EP-2467367-A1 | 3-TRIAZOLYLPHENYL-SUBSTITUTED SULFIDE DERIVATIVES FOR USE AS ACARICIDES AND INSECTICIDES | Bayer CropScience AG (DE) | 2012-06-27 | — | — | EP | claimed |
| US-20120027741-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE AG (DE) | 2012-02-02 | — | — | US | claimed |
| EP-2398326-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | Bayer CropScience AG (DE) | 2011-12-28 | — | — | EP | claimed |
| US-7934888-B2 | Marine anti-foulant system and methods for using same | VIV SUPPRESSION, INC. (US) | 2011-05-03 | — | — | US | claimed |
| WO-2011020567-A1 | 3-TRIAZOLYLPHENYL-SUBSTITUTED SULFIDE DERIVATIVES FOR USE AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | WO | claimed |
| WO-2010094728-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | WO | claimed |
| US-20090185867-A1 | MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME | ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL | 2009-07-23 | — | — | US | claimed |
| EP-2014167-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027741-A1 | PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE | DDT, TH, PRDX5 | CHRM1 1385/4885ADRA1A 4718/4885KDM4E 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.