Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Oxyquinoline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.81 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | COMT | P21964 | 3/20 | 0.81 |
| ▸ | MMP2 | P08253 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | METAP2 | P50579 | 1/20 | 0.81 |
| ▸ | METAP1 | P53582 | 1/20 | 0.81 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL11030481 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL29390000 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL11030474 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL9625423 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL48928 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL29598375 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL324753 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL11030477 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL406261 | 1.00 | KDM4E (1.00) | KDM4EALOX12COMTMMP2TSHR | |
| Oxyquinoline SCHEMBL6081972 | 0.98 | KDM4E (0.96) | KDM4EALOX12COMTMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120130470-A | Processing method for quick dyeing and fresh-keeping cooperative treatment of cut flowers of starfish and special preparation | 云南花益美生物科技有限责任公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119949225-A | Method for promoting flowers of cut flowers of starfish after picking | 云南花益美生物科技有限责任公司 | 2025-05-09 | — | — | CN | claimed |
| US-20250057877-A1 | MULTIPLE USE WOUND AND HEALING CREAM | COLEMAN TERRIS VIOLA (US) | 2025-02-20 | — | — | US | claimed |
| CN-118435802-A | Method for prolonging ornamental period of cut peony flowers | 甘肃省农业科学院林果花卉研究所 | 2024-08-06 | — | — | CN | claimed |
| CN-115152455-B | Method for producing cut lotus flowers | 苏州市农业科学院 | 2023-09-22 | — | — | CN | claimed |
| CN-122011884-A | Self-repairing/corrosion early warning dual-functional coating based on corrosion cathode micro-area environment response release | 西南交通大学 | 2026-05-12 | — | — | CN | disclosed |
| EP-4676925-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2026-01-14 | — | — | EP | disclosed |
| US-20250388630-A1 | FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA | SPOGEN BIOTECH INC (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4655284-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2025-12-03 | — | — | EP | disclosed |
| CN-120982502-A | High-openness starfish cut flower anti-aging pretreatment liquid based on water-energy-ethylene synergistic regulation and control and negative pressure permeation treatment method thereof | 云南花益美生物科技有限责任公司 | 2025-11-21 | — | — | CN | disclosed |
| WO-2025235840-A1 | ECHINOCANDIN-LIKE AND BORON-CONTAINING ECHINOCANDIN COMPOUNDS AND THEIR USE AS AGROCHEMICAL FUNGICIDES | 5METIS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| EP-4646403-A1 | NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-12 | — | — | EP | disclosed |
| CN-113749088-B | Peony cut flower vase preservative solution | 北京林业大学 | 2022-04-29 | — | — | CN | disclosed |
| WO-2022053567-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-17 | — | — | WO | disclosed |
| WO-2022049498-A1 | FORMULATIONS AND METHODS FOR REGULATING AND STIMULATING PLANT GROWTH | UPL LIMITED (IN) | 2022-03-10 | — | — | WO | disclosed |
| WO-2022048988-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-10 | — | — | WO | disclosed |
| WO-2022043576-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-03 | — | — | WO | disclosed |
| EP-3952652-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2022-02-16 | — | — | EP | disclosed |
| EP-3945824-A1 | COLLOIDAL SILVER-BASED COMPOSITIONS AND METHODS OF USE THEREOF FOR PREVENTING AND CONTROLLING PLANT DISEASES | Clearleaf Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2022017975-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388630-A1 | FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA | MAX, SEC62, GHITM | CHRM1 4831/4885ADRA1A 4874/4885KDM4E 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.