SCHEMBL3247629

SCHEMBL3247629

Nc1ccc(-c2cccc3sc(SS)nc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.40
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
KIT P10721 2/20 0.37
KDR P35968 2/20 0.37
FLT3 P36888 2/20 0.37
ALDH1A1 P00352 3/20 0.34
PDPK1 O15530 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.34
PDE10A Q9Y233 1/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
LIMK1 P53667 1/20 0.33
KDM4E B2RXH2 3/20 0.33
GAA P10253 3/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3247625 0.88 ALDH1A1 (0.42) APPMMP9MMP8KITKDR
SCHEMBL28174501 0.78 APP (0.58) APPMMP9MMP8ALDH1A1SMN1; SMN2
SCHEMBL4460654 0.73 ENPP1 (0.42) KDRALDH1A1SMN1; SMN2LMNALIMK1
SCHEMBL1771056 0.73 FBP1 (0.50) KDRALDH1A1LIMK1CYP3A4CYP1A2
SCHEMBL83284 0.73 PSMD14 (0.37) ALDH1A1PDPK1SMN1; SMN2LMNAPDE10A
SCHEMBL7040019 0.71 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2LMNAKDM4EGAA
SCHEMBL4460658 0.70 ENPP1 (0.39) KDRALDH1A1SMN1; SMN2LIMK1NPC1
SCHEMBL3179505 0.69 APP (0.51) APPMMP9MMP8ALDH1A1SMN1; SMN2
SCHEMBL1806582 0.68 ALDH1A1 (0.56) KDRALDH1A1PDPK1SMN1; SMN2LMNA
SCHEMBL3247624 0.68 ALDH1A1 (0.47) ALDH1A1PDPK1SMN1; SMN2LMNAPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1225205-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-10-06 EP disclosed
EP-1942156-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-04-14 EP disclosed
EP-1942156-A1 Carbon black reacted with diazonium salts and products Cabot Corporation (US) 2008-07-09 EP disclosed
US-7294185-B2 In absence of exterior applies electrical current; wear resistance CABOT CORPORATION (US) 2007-11-13 US disclosed
EP-0799281-B2 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2006-03-29 EP disclosed
US-20050034629-A1 In absence of exterior applies electrical current; wear resistance BELMONT JAMES A (US) 2005-02-17 US disclosed
US-6740151-B2 IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT TO REDUCE THE DIAZONIUM SALT AND ATTACH AN ORGANIC GROUP; IMPROVED ABRASION RESISTANCE. CABOT CORPORATION 2004-05-25 US disclosed
US-20030095914-A1 In the absence of an externally applied electric current sufficient to reduce the diazonium salt and attach an organic group; improved abrasion resistance. BELMONT JAMES A (US) 2003-05-22 US disclosed
US-6494946-B1 PROCESSES FOR PREPARING A CARBON BLACK PRODUCT HAVING AN ORGANIC GROUP ATTACHED TO THE CARBON BLACK. IN ONE PROCESS AT LEAST ONE DIAZONIUM SALT REACTS WITH A CARBON BLACK IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT CABOT CORPORATION 2002-12-17 US disclosed
EP-0799281-B1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2002-07-24 EP disclosed
EP-1225205-A2 Carbon black reacted with diazonium salts and products CABOT CORPORATION (US) 2002-07-24 EP disclosed
US-6042643-A AS PIGMENT TO COLOR PLASTICS, PAPER, TEXTILE, RUBBER, AQUEOUS INKS CABOT CORPORATION (US) 2000-03-28 US disclosed
US-5900029-A COLORING FIBER OR TEXTILE CABOT CORPORATION (US) 1999-05-04 US disclosed
US-5851280-A Reaction of carbon black with diazonium salts, resultant carbon black products and their uses CABOT CORPORATION (US) 1998-12-22 US disclosed
EP-0799281-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1997-10-08 EP disclosed
WO-1996018688-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed