Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CEL | P19835 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830749 | 0.90 | BCHE (0.61) | BCHESIGMAR1SLC18A2ATMNPSR1 | |
| SCHEMBL3247871 | 0.81 | ATM (0.58) | BCHESIGMAR1SLC18A2ATMNPSR1 | |
| SCHEMBL28926014 | 0.79 | CYP2D6 (0.58) | BCHESIGMAR1SLC18A2ATMNPSR1 | |
| SCHEMBL19465402 | 0.79 | BCHE (0.49) | BCHESIGMAR1SLC18A2ATMNPSR1 | |
| SCHEMBL1581925 | 0.78 | HDAC3 (0.45) | BCHESIGMAR1SLC18A2 | |
| SCHEMBL12203963 | 0.78 | SIGMAR1 (0.56) | BCHESIGMAR1SLC18A2 | |
| SCHEMBL22137299 | 0.77 | CEL (0.46) | BCHESIGMAR1SLC6A4CEL | |
| SCHEMBL16593849 | 0.77 | CYP1A2 (0.52) | BCHESIGMAR1CEL | |
| SCHEMBL5830948 | 0.76 | GPR84 (0.59) | SIGMAR1 | |
| SCHEMBL9800436 | 0.76 | CYP1A2 (0.58) | SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531382-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-03-17 | — | — | EP | disclosed |