Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642142 | 0.81 | HTR6 (1.00) | HTR6HTR1AHTR7KDM4EUBE2N | |
| SCHEMBL18125259 | 0.78 | HTR6 (0.61) | HTR6HTR1AHTR7KDM4EUBE2N | |
| SCHEMBL22339784 | 0.77 | KDM4E (0.66) | HTR6KDM4EUBE2N | |
| SCHEMBL5413550 | 0.75 | KDM4E (0.63) | HTR6KDM4EUBE2N | |
| SCHEMBL3248158 | 0.75 | HTR6 (1.00) | HTR6HTR1AHTR7 | |
| SCHEMBL22339785 | 0.73 | KDM4E (0.60) | HTR6KDM4EUBE2N | |
| SCHEMBL28528958 | 0.72 | L3MBTL1 (0.61) | HTR6KDM4EUBE2N | |
| SCHEMBL13504568 | 0.70 | HTR6 (0.48) | HTR6HTR7 | |
| SCHEMBL5253195 | 0.70 | HTR6 (1.00) | HTR6HTR1A | |
| SCHEMBL6089916 | 0.69 | KDM4E (0.59) | HTR6KDM4EUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184064-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-05-12 | — | — | EP | disclosed |