Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740584 | 0.86 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL31346403 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL9181204 | 0.84 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL14997791 | 0.82 | MEN1 (0.33) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24872768 | 0.81 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL165754 | 0.81 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL14557124 | 0.81 | TSHR (0.33) | MEN1KMT2AALDH1A1TSHRTHRB | |
| SCHEMBL15740594 | 0.81 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL20348152 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL862703 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101547907-B | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV | 2013-01-02 | — | — | CN | claimed |
| EP-2099762-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-12 | — | — | EP | claimed |
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (NJ) | 2010-03-18 | — | — | US | claimed |
| CN-101547907-A | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2009-09-30 | — | — | CN | claimed |
| EP-2099762-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-16 | — | — | EP | claimed |
| WO-2008068266-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | WO | claimed |
| US-20130140064-A1 | METHOD OF MAKING ELECTRONIC DEVICES USING SELECTIVE DEPOSITION | BANK OF AMERICA, N.A., AS AGENT | 2013-06-06 | — | — | US | disclosed |
| CN-101547907-B | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV | 2013-01-02 | — | — | CN | disclosed |
| EP-2099762-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-12 | — | — | EP | disclosed |
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (NJ) | 2010-03-18 | — | — | US | disclosed |
| US-20090291938-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| CN-101547907-A | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2009-09-30 | — | — | CN | disclosed |
| EP-2099762-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009067547-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
| WO-2008068266-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291938-A1 | POLO-LIKE KINASE INHIBITORS | PLK1, PLK2, POLK | MEN1 3731/4885KMT2A 1796/4885ALDH1A1 4009/4885 |
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | NQO2, NDUFB5, NDUFB7 | MEN1 3590/4885KMT2A 3475/4885ALDH1A1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.