SCHEMBL3248433

SCHEMBL3248433

CCC(CC)C(=CC1CC2CCC1C2)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HSD11B1 P28845 1/20 0.33
ATM Q13315 1/20 0.32
EPHX2 P34913 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.30
HPGD P15428 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245018 0.83 POLB (0.39) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL7253567 0.80 POLB (0.37) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL245976 0.76 POLB (0.42) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL158980 0.74 POLB (0.41) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL32688568 0.71 POLB (0.40) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL6396833 0.71 POLB (0.40) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL7708642 0.70 POLB (0.39) POLBATMEPHX2HPGDALDH1A1
SCHEMBL703642 0.70 POLB (0.42) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL32689055 0.70 KMT2A (0.39) POLBKMT2AMEN1NPC1RAB9A
SCHEMBL562823 0.70 POLB (0.39) POLBKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1739667-B1 OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO LTD (JP) 2010-07-28 EP disclosed
US-20070297315-A1 Optical Recording Medium MITSUBISHI KAGAKU MEDIA COL., LTD. (JP) 2007-12-27 US disclosed
EP-1739667-A1 OPTICAL RECORDING MEDIUM Mitsubishi Kagaku Media Co., Ltd. (JP) 2007-01-03 EP disclosed