SCHEMBL7253567

SCHEMBL7253567

CC(C(=O)O)C(=CC1CC2CCC1C2)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ATM Q13315 1/20 0.33
NPC1 O15118 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245018 0.87 POLB (0.39) POLBLMNAHPGDSMN1; SMN2ATM
SCHEMBL3248433 0.80 POLB (0.36) POLBLMNAHPGDSMN1; SMN2ATM
SCHEMBL158980 0.75 POLB (0.41) POLBLMNAHPGDSMN1; SMN2ATM
SCHEMBL245976 0.71 POLB (0.42) POLBHPGDSMN1; SMN2ATMNPC1
SCHEMBL7708642 0.71 POLB (0.39) POLBHPGDATM
SCHEMBL32688585 0.69 POLB (0.42) POLBLMNAHPGDSMN1; SMN2ATM
SCHEMBL32688828 0.69 POLB (0.36) POLBLMNAHPGDSMN1; SMN2ATM
SCHEMBL6396833 0.69 POLB (0.40) POLBHPGDSMN1; SMN2ATMNPC1
SCHEMBL7940071 0.68 POLB (0.40) POLBHPGDATM
SCHEMBL703642 0.68 POLB (0.42) POLBLMNAHPGDSMN1; SMN2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM POLB 2346/4885LMNA 202/4885HPGD 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.