Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.55 |
| ▸ | F7 | P08709 | 16/20 | 0.55 |
| ▸ | F3 | P13726 | 16/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264482 | 0.85 | F2 (0.59) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL6423667 | 0.78 | F2 (0.71) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL3241754 | 0.72 | F2 (0.58) | F2PRSS1 | |
| SCHEMBL7025534 | 0.71 | TPSAB1 (0.49) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL3249068 | 0.71 | SMN1; SMN2 (0.50) | TPSAB1 | |
| SCHEMBL7024770 | 0.71 | TPSAB1 (0.50) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7026586 | 0.70 | TPSAB1 (0.50) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL3247707 | 0.69 | F2 (0.60) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7025014 | 0.69 | TPSAB1 (0.47) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL5885720 | 0.68 | F2 (0.58) | F2F7F3PRSS1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589029-B1 | Pyrazinone protease inhibitors | ORTHO MCNEIL PHARM INC (US) | 2010-03-17 | — | — | EP | disclosed |