Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748890 | 0.77 | CYP3A4 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL9547513 | 0.72 | SMN1; SMN2 (0.52) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL3249158 | 0.71 | RECQL (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL7589098 | 0.69 | RECQL (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL5607442 | 0.68 | HIF1A (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL11035726 | 0.68 | SMN1; SMN2 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL3249147 | 0.68 | TSHR (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL6276750 | 0.67 | SMN1; SMN2 (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL4595472 | 0.67 | SMN1; SMN2 (0.60) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL | |
| SCHEMBL16447677 | 0.67 | HIF1A (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |