Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162490 | 0.90 | ALDH1A1 (0.48) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL3482670 | 0.85 | MEN1 (0.50) | SMN1; SMN2ALDH1A1TSHRPTPRBPTPN2 | |
| SCHEMBL15671357 | 0.84 | MMP8 (0.40) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL7742277 | 0.77 | RECQL (0.42) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL13270387 | 0.76 | ALDH1A1 (0.35) | RECQLCYP3A4SMN1; SMN2ALDH1A1MMP8 | |
| SCHEMBL1695173 | 0.75 | SMN1; SMN2 (0.49) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL11748890 | 0.74 | CYP3A4 (0.47) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL8578234 | 0.74 | SMN1; SMN2 (0.43) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL2711802 | 0.73 | AKT1 (0.46) | RECQLCYP3A4ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1697372 | 0.73 | ALDH1A1 (0.48) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |