Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351965 | 0.89 | CA12 (0.45) | RECQLCYP3A4CYP1A2ALDH1A1MAPK1 | |
| SCHEMBL16088511 | 0.79 | ALDH1A1 (0.61) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL8602941 | 0.73 | ENPEP (0.53) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL11748890 | 0.72 | CYP3A4 (0.47) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL23256417 | 0.70 | MAPT (0.46) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL20241701 | 0.70 | SMN1; SMN2 (0.58) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL22406298 | 0.70 | SMN1; SMN2 (0.44) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL20241700 | 0.70 | SMN1; SMN2 (0.58) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL8999172 | 0.70 | MMP8 (0.54) | RECQLCYP3A4CYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL6351491 | 0.70 | CA12 (0.43) | RECQLCYP3A4CYP1A2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020187981-A1 | Heterocyclic amines having central nervous system activity | ROMERO ARTHUR GLENN (US) | 2002-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187981-A1 | Heterocyclic amines having central nervous system activity | CNR1, CNR2, OPRD1 | RECQL 1168/4885CYP3A4 692/4885CYP1A2 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.