Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249745 | 0.85 | GAA (0.49) | MAPK1TAAR1ESR2ESR1MAPT | |
| SCHEMBL3240895 | 0.79 | TAAR1 (0.43) | MAPK1TAAR1ESR2ESR1MAPT | |
| SCHEMBL3120660 | 0.78 | GAA (0.49) | MAPK1TAAR1MAPTTDP1GAA | |
| SCHEMBL3119103 | 0.78 | GAA (0.42) | ESR2ESR1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3237347 | 0.75 | GAA (0.48) | MAPK1MAPTTDP1GAAALDH1A1 | |
| SCHEMBL13521762 | 0.73 | TAAR1 (0.41) | TAAR1ESR2ESR1MAPTTDP1 | |
| SCHEMBL3241489 | 0.73 | TSHR (0.46) | MAPK1TAAR1ESR2ESR1MAPT | |
| SCHEMBL3126815 | 0.73 | GAA (0.51) | MAPK1ESR2ESR1MAPTTDP1 | |
| SCHEMBL3252753 | 0.72 | TSHR (0.44) | MAPK1TAAR1ESR2ESR1MAPT | |
| SCHEMBL13521636 | 0.72 | TSHR (0.50) | MAPK1TAAR1ESR2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |