Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 14/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.64 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.64 |
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241833 | 0.82 | GRM5 (0.48) | SYKAURKBINCENPGRM5CHRNA7 | |
| SCHEMBL13575392 | 0.81 | L3MBTL1 (0.60) | FYNAVPR2OXTRAVPR1A | |
| SCHEMBL3245556 | 0.79 | KDM4E (0.47) | SYKAURKBINCENPGRM5 | |
| SCHEMBL23406003 | 0.79 | GRM5 (0.48) | SYKAURKBINCENPGRM5 | |
| SCHEMBL29744012 | 0.79 | GRM5 (0.48) | SYKAURKBINCENPGRM5 | |
| SCHEMBL3237662 | 0.78 | SYK (0.54) | SYKAURKBINCENP | |
| SCHEMBL13661860 | 0.75 | SYK (0.54) | SYKAURKBINCENPGRM5 | |
| SCHEMBL1528197 | 0.74 | HSD17B10 (0.53) | SYKAURKBINCENPCHRNA7 | |
| SCHEMBL28039454 | 0.73 | SYK (0.77) | SYKAURKBINCENP | |
| SCHEMBL3645148 | 0.73 | GABRA5 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |