Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484951 | 0.79 | PTGDR2 (0.44) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL3266556 | 0.76 | KMT2A (0.35) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL2282152 | 0.74 | PTGDR2 (0.45) | MEN1LMNAKMT2AMAPTHTT | |
| SCHEMBL2753212 | 0.74 | MAPK1 (0.55) | SLC6A4HRH3HTR2AKCNH2MEN1 | |
| SCHEMBL2753829 | 0.71 | MAPK1 (0.37) | SLC6A4HTR2AKCNH2MEN1LMNA | |
| SCHEMBL3485703 | 0.69 | PTGDR2 (0.43) | SLC6A4LMNAKMT2AHTR6MAPK1 | |
| SCHEMBL9686778 | 0.66 | LMNA (0.35) | LMNAKMT2AHTTMAPK1L3MBTL1 | |
| SCHEMBL5214192 | 0.66 | MAOB (0.41) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL1568289 | 0.66 | QRFPR (0.47) | MEN1LMNAKMT2AQRFPRMAPT | |
| SCHEMBL4909322 | 0.66 | MAPT (0.47) | SLC6A4SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003127-A2 | ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |