SCHEMBL3249669

SCHEMBL3249669

O=S(=O)(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 9/20 0.73
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
AKR1B1 P15121 1/20 0.50
RECQL P46063 1/20 0.50
MAOA P21397 1/20 0.49
LOX P28300 1/20 0.49
F2 P00734 1/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
FEN1 P39748 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547461 0.87 CA1 (0.68) HTR6CA1CA2CA9KMT2A
SCHEMBL10775871 0.85 HTR6 (1.00) HTR6CA1CA2CA9KMT2A
SCHEMBL7475947 0.85 HTR6 (0.65) HTR6CA1CA2CA9KMT2A
SCHEMBL6828570 0.85 HTR6 (0.70) HTR6CA1CA2CA9KMT2A
SCHEMBL9413714 0.85 HTR6 (0.70) HTR6CA1CA2CA9KMT2A
SCHEMBL9587035 0.85 HTR6 (0.70) HTR6CA1CA2CA9KMT2A
SCHEMBL7175789 0.85 CA1 (0.65) HTR6CA1CA2CA9KMT2A
SCHEMBL7540102 0.84 HTR6 (0.64) HTR6CA1CA2CA9KMT2A
SCHEMBL10451361 0.83 HTR6 (0.68) HTR6CA1CA2CA9KMT2A
SCHEMBL30999723 0.82 HTR6 (0.62) HTR6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162995-A1 Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases DOW GLOBAL TECHNOLOGIES LLC 2003-08-28 US claimed
CN-1419538-A Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases ENICHEM SPA (IT) 2003-05-21 CN claimed
JP-60054883-A None JP disclosed
EP-3681933-B1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA (US) 2024-05-15 EP disclosed
CN-116496136-A Diaryl sulfone compound and preparation method thereof 华北水利水电大学 2023-07-28 CN disclosed
US-11359120-B2 Polymer-metal junction SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-14 US disclosed
US-20210122953-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALITY POLYMERS USA, LLC 2021-04-29 US disclosed
EP-3681933-A1 POLYMER-METAL JUNCTION Solvay Specialty Polymers USA, LLC (US) 2020-07-22 EP disclosed
CN-111263786-A Polymer-metal joint 索尔维特殊聚合物美国有限责任公司 2020-06-09 CN disclosed
EP-3248230-B1 USE OF ORGANIC MOLECULES IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2020-05-06 EP disclosed
EP-3247772-B1 SYMMETRICAL ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2019-10-16 EP disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0068695-A1 Blends of poly (parabanic acids) with other polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-05 EP disclosed
EP-0061013-A1 Process for the preparation of polyisocyanates BAYER AG (DE) 1982-09-29 EP disclosed
EP-0057104-A2 Polymers containing 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or sulfoxides EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-08-04 EP disclosed
US-4325860-A Polymers characterized by 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or aromatic sulfoxides EXXON RESEARCH & ENGINEERING CO. (US) 1982-04-20 US disclosed
US-4150025-A COLORING TEIJIN LIMITED (JP) 1979-04-17 US disclosed
US-4069205-A FROM BI- OR TRI-PHENYLENE SULFIDE, AROMATIC ETHER, AND ISOPHTHALOYL OR TEREPHTHALOYL HALIDE UNIVERSITY PATENTS, INC. (US) 1978-01-17 US disclosed
US-3948788-A DIARYL SULFONES, HALOGEN-FREE AROMATIC COMPOUNDS MONSANTO COMPANY (US) 1976-04-06 US disclosed
US-3948787-A DIARYL SULFONES, CARBOXYLIC ESTERS MONSANTO COMPANY (US) 1976-04-06 US disclosed