SCHEMBL7540102

SCHEMBL7540102

O=C(O)c1ccc(S(=O)(=O)c2cccc3ccccc23)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.64
TSHR P16473 2/20 0.62
SLC16A3 O15427 2/20 0.50
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
P4HTM Q9NXG6 1/20 0.47
KMT2A Q03164 1/20 0.46
DHODH Q02127 1/20 0.46
NAMPT P43490 1/20 0.46
POLB P06746 1/20 0.46
HSD17B10 Q99714 1/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
CA12 O43570 1/20 0.44
CA3 P07451 1/20 0.44
CA6 P23280 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA5A P35218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3249669 0.84 HTR6 (0.73) HTR6CA1CA2CA9KMT2A
SCHEMBL8162975 0.83 HTR6 (0.67) HTR6TSHRCA1CA2CA9
SCHEMBL6828570 0.81 HTR6 (0.70) HTR6CA1CA2CA9KMT2A
SCHEMBL7196091 0.79 APEX1 (0.48) HTR6TSHRCA1CA2CA9
SCHEMBL7545258 0.79 LDHA (0.53) HTR6TSHRCA1CA2CA9
SCHEMBL7191147 0.78 POLB (0.58) TSHRCA1CA2CA9KMT2A
SCHEMBL9587035 0.78 HTR6 (0.70) HTR6CA1CA2CA9KMT2A
SCHEMBL9413714 0.78 HTR6 (0.70) HTR6CA1CA2CA9KMT2A
SCHEMBL10775871 0.78 HTR6 (1.00) HTR6TSHRCA1CA2CA9
SCHEMBL15762086 0.77 TSHR (1.00) TSHRSLC16A3P4HTMHSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 HTR6 2178/4885TSHR 4831/4885SLC16A3 3451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.