Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178726 | 0.82 | CYP2A6 (0.42) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8148539 | 0.82 | CYP2A6 (0.42) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL239122 | 0.79 | CYP2A6 (0.37) | ALDH1A1CYP2A6CYP1A2CYP3A4TSHR | |
| SCHEMBL4609078 | 0.77 | MAPK1 (0.39) | ALDH1A1CYP2A6RAB9ASMN1; SMN2DCUN1D1 | |
| SCHEMBL3240933 | 0.77 | CYP2A6 (0.39) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3246275 | 0.77 | NPC1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL668159 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2A6SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL10501303 | 0.77 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL667984 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CYP2A6RAB9ASMN1; SMN2TSHR | |
| SCHEMBL3241635 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1473297-B1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEM IND CO (JP) | 2009-10-14 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| US-7250535-B2 | Process for producing tertiary phosphine | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HOLLO CHEMICAL INDUSTRY CO., LTD (JP) | 2006-01-26 | — | — | US | disclosed |
| EP-1473297-A1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HRH3, HRH4, HRH1 | ALDH1A1 1764/4885CYP2A6 2988/4885NPC1 4180/4885 |
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | ALDH1A1 874/4885CYP2A6 2385/4885NPC1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.