Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79020 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HSD17B10CYP2A6MEN1KMT2A | |
| SCHEMBL3149589 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HSD17B10BCL2L1MAPK1BACE1 | |
| SCHEMBL239122 | 0.79 | CYP2A6 (0.37) | ALDH1A1HSD17B10HPGDCYP2A6TSHR | |
| SCHEMBL668632 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HSD17B10HPGDCYP2A6MAPK1 | |
| SCHEMBL669473 | 0.78 | DNMT1 (0.38) | ALDH1A1HSD17B10HPGDCYP2A6MAPK1 | |
| SCHEMBL3249728 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HSD17B10HPGDCYP2A6DCUN1D1 | |
| SCHEMBL4609078 | 0.77 | MAPK1 (0.39) | ALDH1A1HSD17B10HPGDCYP2A6MAPK1 | |
| SCHEMBL3240933 | 0.77 | CYP2A6 (0.39) | ALDH1A1HPGDCYP2A6GPR55DCUN1D1 | |
| SCHEMBL27802208 | 0.77 | C1R (0.30) | — | |
| SCHEMBL10501303 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132536-B2 | Triaza- and tetraaza-anthracenedione derivatives, their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-11-07 | — | — | US | claimed |
| US-6555580-B2 | Treating arteriosclerosis and hypercholesterolaemia | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | claimed |
| EP-0409077-B1 | 1-Aza-butadienes and fungicides containing them | BASF AG (DE) | 1993-10-20 | — | — | EP | claimed |
| EP-2502908-B1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-1990844-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | IDEMITSU KOSAN CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-9278926-B2 | Aromatic amine derivative, and organic electroluminescent element comprising same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-08 | — | — | US | disclosed |
| US-9214636-B2 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2015-12-15 | — | — | US | disclosed |
| EP-2085371-B1 | FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE USING THE FLUORANTHENE COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION | IDEMITSU KOSAN CO (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-9120748-B2 | Fluoranthene compound, organic electroluminescence device using the same, and solution containing organic electroluminescence material | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-01 | — | — | US | disclosed |
| US-8932735-B2 | Aromatic amine derivative and organic electroluminescent element comprising the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-01-13 | — | — | US | disclosed |
| EP-2351759-B1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-20090015144-A1 | FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL | IDEMITSU KOSAN CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-2008992-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003135-A2 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE OXIDE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
| EP-1990844-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Idemitsu Kosan Co., Ltd. (JP) | 2008-11-12 | — | — | EP | disclosed |
| US-20080071099-A1 | Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20080004445-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1849778-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE EPOXY COMPOUND, COMPLEX FOR USE IN THE PROCESS, AND PROCESS FOR PRODUCING THE SAME | Japan Science and Technology Agency (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-20070243411-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-0017012-A2 | Dyes and process for the generation of tints based on optionally substituted 2-amino-5-iminopyrrolenines | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004445-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | TYR, MAOA, PRDM9 | ALDH1A1 291/4885HSD17B10 3259/4885HPGD 3635/4885 |
| US-20090015144-A1 | FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL | LEF1, ESD, AFF2 | ALDH1A1 422/4885HSD17B10 2452/4885HPGD 2404/4885 |
| US-20080071099-A1 | Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same | EPRS1, PPOX, POR | ALDH1A1 840/4885HSD17B10 1176/4885HPGD 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.