Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252655 | 0.84 | ROCK2 (0.56) | ROCK2ROCK1 | |
| SCHEMBL3249575 | 0.83 | ROCK2 (0.43) | ROCK2ROCK1GAAALDH1A1HPGD | |
| SCHEMBL3247491 | 0.80 | ROCK2 (0.55) | ROCK2ROCK1 | |
| SCHEMBL3244445 | 0.78 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL3251643 | 0.75 | ROCK2 (0.45) | ROCK2ROCK1GAAHPGDSMN1; SMN2 | |
| SCHEMBL3248059 | 0.74 | ROCK2 (0.57) | ROCK2ROCK1 | |
| SCHEMBL3248261 | 0.74 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL3249765 | 0.71 | ROCK2 (0.51) | ROCK2ROCK1 | |
| SCHEMBL3244463 | 0.71 | ROCK2 (0.42) | ROCK2ROCK1ALDH1A1HPGDKDM4E | |
| SCHEMBL3247209 | 0.70 | ROCK2 (0.52) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |