Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247956 | 0.91 | NR1H4 (0.56) | NR1H4EYA3PTPN1TTRESR1 | |
| SCHEMBL3256165 | 0.91 | NR1H4 (0.56) | NR1H4EYA3PTPN1TTRESR1 | |
| Hydrochloric Acid SCHEMBL6139669 | 0.90 | NR1H4 (0.55) | NR1H4EYA3PTPN1TTRESR1 | |
| SCHEMBL6139604 | 0.88 | PTPN1 (0.52) | NR1H4EYA3PTPN1ESR1PGR | |
| SCHEMBL3255546 | 0.88 | NR1H4 (0.57) | NR1H4EYA3PTPN1TTRESR1 | |
| SCHEMBL3243305 | 0.88 | NR1H4 (0.57) | NR1H4EYA3PTPN1TTRESR1 | |
| SCHEMBL5226741 | 0.87 | EYA3 (0.72) | NR1H4EYA3PTPN1TTRESR1 | |
| SCHEMBL3243262 | 0.87 | ESR1 (0.56) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL3252689 | 0.87 | ESR1 (0.56) | ESR1PGRCHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL6139779 | 0.86 | ABCB11 (0.56) | ESR1PGRCHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315709-B1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |
| EP-1315709-A1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016339-A1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |