Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 5/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.72 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020570 | 0.91 | EYA3 (0.77) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL6140415 | 0.89 | EYA3 (0.60) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL14552011 | 0.88 | EYA3 (0.72) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL3249884 | 0.87 | NR1H4 (0.58) | EYA3PTPN1SLC22A12NR1H4TTR | |
| SCHEMBL5225391 | 0.87 | NR1H4 (0.60) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL6140040 | 0.87 | EYA3 (0.67) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL5671722 | 0.87 | EYA3 (0.67) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL11817673 | 0.87 | EYA3 (0.70) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL4567255 | 0.87 | EYA3 (0.70) | EYA3PTPN1SLC22A12NR1H4CYP2C9 | |
| SCHEMBL3243305 | 0.86 | NR1H4 (0.57) | EYA3PTPN1SLC22A12NR1H4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315710-B1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-04-25 | — | — | EP | disclosed |
| US-6946483-B2 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2005-09-20 | — | — | US | disclosed |
| EP-1315708-B1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2004-08-11 | — | — | EP | disclosed |
| US-20030187060-A1 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | SANOFI (FR) | 2003-10-02 | — | — | US | disclosed |
| EP-1315710-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1315708-A1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016338-A1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |
| WO-2002016340-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187060-A1 | Aminoalkenylbenzoyl-benzofuran or benzothiophene, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT2 | EYA3 3231/4885PTPN1 1876/4885SLC22A12 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.