Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263754 | 0.86 | ROCK2 (0.70) | ROCK2ROCK1 | |
| SCHEMBL3248267 | 0.83 | ROCK2 (0.66) | ROCK2ROCK1 | |
| SCHEMBL3245270 | 0.81 | ROCK2 (0.76) | ROCK2 | |
| SCHEMBL3244603 | 0.81 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL28335753 | 0.79 | ALDH1A1 (0.59) | MAPT | |
| SCHEMBL3246002 | 0.76 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL3243298 | 0.75 | ROCK2 (0.70) | ROCK2ROCK1 | |
| SCHEMBL18741163 | 0.75 | HPGD (0.66) | ROCK2ROCK1MAPTSCN2ASCN10A | |
| SCHEMBL3130229 | 0.74 | ROCK2 (0.71) | ROCK2ROCK1 | |
| SCHEMBL1647259 | 0.73 | PRKACA (0.67) | ROCK2ROCK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |