Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140406 | 0.74 | DAGLA (0.40) | GBA1GAAKMT2AMEN1HTT | |
| SCHEMBL20567938 | 0.72 | MEN1 (0.39) | KMT2AMEN1HTTKDM4E | |
| SCHEMBL28628837 | 0.72 | ALDH1A1 (0.39) | KMT2AMEN1POLBHTTKDM4E | |
| SCHEMBL5113646 | 0.72 | ERCC5 (0.43) | HDAC6 | |
| SCHEMBL3242666 | 0.71 | HPGD (0.44) | MYCHPGDKMT2AMEN1POLB | |
| SCHEMBL17371937 | 0.71 | MEN1 (0.50) | KMT2AMEN1POLBCYP2C9SMN1; SMN2 | |
| SCHEMBL2175726 | 0.71 | HDAC6 (0.45) | CYP2A6HPGDKMT2AMEN1POLB | |
| SCHEMBL9146212 | 0.71 | NPC1 (0.55) | GBA1CYP2A6GAAKMT2AMEN1 | |
| SCHEMBL24964516 | 0.70 | DYRK1A (0.47) | HPGDHDAC6CYP2C9HTT | |
| SCHEMBL30661687 | 0.70 | DYRK1A (0.47) | HPGDHDAC6CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |