SCHEMBL27140406

SCHEMBL27140406

CC(C)(C)N(Cc1nc2cnccc2o1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 1/20 0.40
FAAH O00519 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
GBA1 P04062 1/20 0.36
GAA P10253 1/20 0.35
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
PTGER2 P43116 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 3/20 0.32
TRPM8 Q7Z2W7 1/20 0.32
USP2 O75604 1/20 0.32
TSHR P16473 1/20 0.32
LATS1 O95835 2/20 0.32
RAB9A P51151 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3249923 0.74 GBA1 (0.36) MEN1KMT2AGBA1GAAHTT
SCHEMBL27150194 0.71 ROCK2 (0.43) DAGLAFAAHGAAL3MBTL1MAPT
SCHEMBL12819613 0.71 GAA (0.45) DAGLAFAAHMEN1KMT2AGBA1
SCHEMBL17371937 0.71 MEN1 (0.50) MEN1KMT2ALMNAALDH1A1L3MBTL1
SCHEMBL1273108 0.71 LMNA (0.42) DAGLAFAAHGAALMNAMAPT
SCHEMBL30759244 0.70 LATS1 (0.46) FAAHGAAALDH1A1HTTMAPT
SCHEMBL28628837 0.70 ALDH1A1 (0.39) MEN1KMT2ALMNAALDH1A1L3MBTL1
SCHEMBL20567938 0.70 MEN1 (0.39) MEN1KMT2ALMNAALDH1A1L3MBTL1
SCHEMBL22075606 0.68 LATS1 (0.49) MEN1KMT2AGAALMNAALDH1A1
SCHEMBL1273107 0.68 DAGLA (0.37) DAGLAFAAHMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S DAGLA 3514/4885FAAH 1090/4885MEN1 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.