Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20567938 | 0.85 | MEN1 (0.39) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL17371937 | 0.77 | MEN1 (0.50) | ALDH1A1POLBMAPTLMNAMEN1 | |
| SCHEMBL13285102 | 0.75 | SLC6A4 (0.48) | ALDH1A1POLBMAPTLMNAKDM4E | |
| SCHEMBL3249923 | 0.72 | GBA1 (0.36) | POLBKDM4EMEN1HTTKMT2A | |
| SCHEMBL8746918 | 0.72 | NAPRT (0.47) | MAPTKDM4EGPR119KDM4CSIRT3 | |
| SCHEMBL1362512 | 0.71 | LMNA (0.46) | ALDH1A1POLBMAPTLMNAMEN1 | |
| SCHEMBL1041865 | 0.70 | TDP1 (0.39) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL5514821 | 0.70 | KMT2A (0.48) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL27140406 | 0.70 | DAGLA (0.40) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL23391421 | 0.69 | BRD4 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | disclosed |